Maney Editor wins Royal Society Award
Professor Mohan Edirisinghe, Dr Eleanor Stride and Uthumanku Farook of University College London, UK, have won the Engineering and Physical Sciences Research Council (EPSRC) Journal of the Royal Society Interface Award for their research on controlled microbubble preparation. The work has significant potential for applications in medical imaging and targeted drug delivery. Professor Edirisinghe is Editor of the Institute’s journal Advances in Applied Ceramics: Structural, Functional and Bioceramics, and also of the recently launched journal Bubble Science, Engineering and Technology.
To celebrate its fifth year of publication, the Journal of the Royal Society Interface has honoured what has been judged the best research article published in the journal over that period. Offered in conjunction with the Engineering and Physical Sciences Research Council (EPSRC), the prize consisted of an award of £5,000 to the authors plus a student educational travel award of £2,000.The prize was awarded to Professor Mohan Edirisinghe, Dr Eleanor Stride and Mr U Farook, University College London, UK, for their paper ‘Preparation of suspensions of phospholipid-coated microbubbles by coaxial electrohydrodynamic atomization’ (J. R. Soc. Interface. 6 March 2009 6, (32), 271–277). Two runners-up were selected by the judges: these were papers by Rhoda Hawkins and Tom McLeish of University of Leeds and Stephen Eichhorn and William Sampson of Manchester University.
Microbubbles generally comprise a gas core stabilised by a protein, lipid or polymer shell. A major driver of research in this area is the increasing potential of microbubbles as contrast agents in medical ultrasound imaging and as vehicles for targeted drug delivery. These applications require the precise control of microbubble size and properties, which still represent a considerable research challenge. Professor Edirisinghe's paper describes a method of microbubble preparation, scalable for commercial use, which combines the controlled flow of liquid and air under the application of an electric field. Using this method of preparation, the UCL researchers were able to generate phospholipid-coated microbubbles with a mean diameter of 6.6 μm and a standard deviation of 2.5 μm.
The multidisciplinary field of bubbles research is currently showing strong activity. As well as the medical and therapeutic applications highlighted above, bubbles play important roles in food processing, materials engineering, environmental engineering and mineral processing. In recognition of this trend, Professor Edirisinghe has founded a new journal, Bubble Science, Engineering and Technology, which will publish high quality research on the generation, properties and applications of bubbles in the life and physical sciences, engineering and medicine. The co-Editor is Professor Carlos Martinez, Purdue University IN, USA. Launched in mid 2009, the first double-issue of the journal includes a series of commissioned reviews surveying key areas of bubbles research. Coverage includes approaches to bubble generation, recent progress in the development of microbubbles for biomedical applications, the physical chemistry of medical microbubble lipid shells, bubble coalescence and a further paper on the capabilities of the electrohydrodynamic technique. Volume 1 articles are available to view under a free trial.
Mohan Edirisinghe has been Editor of the Institute’s journal Advances in Applied Ceramics since 2004, successfully relaunching it in 2005 with a focus on structural, biomedical and functional ceramics in 2005. He was the recipient of the Institute’s Kroll Medal and Prize in 2009 for his research over the past 20 years into ceramics processing and forming.
Visit The Royal Society for further information on the EPSRC Journal of the Royal Society.
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