Kate Thornton, The University of Manchester, North West finalist
Developing Synthetic Scaffolds for the Culture of Embryonic Stem Cells
Embryonic stem (ES) cells have potential within regenerative medicine. However, clinical application of these cells is not yet possible due to a number of factors, including the conditions required to grow the cells. For ES cells to be used therapeutically, they must be cultured in a well defined synthetic environment.
A design criterion has been developed to provide the cells with their ideal man-made scaffold for growth and/or differentiation, suitable substrata for a range of cell types. With careful development they may also be suitable for ES cells, which have hydrogels formed from self-assembling peptides, which are a specific requirement of their micro-environment.
